What is the Difference Between CBDV and CBD?
We have talked about CBD plenty of times but have we told you about another non-intoxicating cannabinoid with similar effects such as CBD? Let us introduce you to CBDV. CBDV (Cannabidivarin) and CBD are almost the same but the differences between them are enough to study them separately. While scientists believe that CBDV is effective in addressing issues that CBD isn’t able to, we take you through its concept, how it is different from CBD, and how it works with our bodies. What is CBDV? CBDV (Cannabidivarin) is similar to CBD but not the same. It was first isolated in 1969 and found to be a natural variant of CBD. Cannabidivarin is also found in cannabis plants but in much lower concentrations. Scientists have discovered more than 100 unique cannabinoids in cannabis and hemp. Like CBD, it doesn’t bind with cannabinoid receptors but influences their activities indirectly to induce intoxication-free therapeutic CBDV effects. Most of these substances are simply variations of a few core compounds. There are a few different types of CBD and Cannabidivarin is one of the well-known types. What is CBD? CBD (Cannabidiol) is one of the most abundant cannabinoids found in the cannabis plant. It interacts with endocannabinoid receptors in the body to produce therapeutic results without causing any intoxicating effects. As of 2018, CBD products are no longer controlled substances if they are made from hemp as hemp is a word used to describe any cannabis plant that has less than 0.3% THC. Difference Between CBDV and CBD There’s not a major difference between CBD vs CBDV. They are just distinguished from each other by comparing the side chains of both molecules. Cannabidivarin has a shortened, three-carbon-long, propyl side chain whereas CBD has a longer, five-carbon-long, pentyl side chain. CBDV might make some nerve cells less active, thereby relieving seizures, swelling, pain, and related conditions. Whereas CBD is used to treat certain seizure disorders and to reduce insomnia, anxiety, pain, and other conditions. While both CBDV and CBD can offer non-intoxicating therapeutic benefits, CBD is more popular and researched, making it a no-brainer choice for those who seek a natural supplement to improve general wellness. How Does CBDV Work in the System? CBDV works in the system in almost the same way as CBD but has a greater affinity for certain neuroreceptors and lesser for others. For example, CBDV mainly binds to the neuroreceptors TRPV1, TRPV2, and TRPA1 – which are crucial for regulating body processes such as temperature sensing, inflammation, and pain perception. Still, not a lot of research is available on the CBDV effects in the human body, to make any solid claims, regarding the exact pharmacodynamics of this cannabinoid. How Does CBD Work in the Body? CBD interacts with receptors in the central nervous system to induce a calming effect. It may also serve as an anti-inflammatory agent and produce pain-relieving effects. Nowadays CBD is becoming more and more popular as an alternative to pharmaceutical drugs to relieve various symptoms. People with anxiety, depression, or pain should include CBD in their routine instead of SSRIs (selective serotonin reuptake inhibitors) as they are highly addictive and have a lot of side effects. What Are the Benefits of CBDV? Let’s have a look at some of the current studies of CBDV cannabinoid benefits: CBDV And Autism Spectrum Disorder (ASD) While still a lot of research is required, Cannabidivarin shows potential for supporting repetitive behavioral and communication problems in children suffering from Autism Spectrum Disorder (ASD). One study also found that CBDV could relieve acute anxiety in participants by boosting GABA levels in the brain and stimulating the neurotransmitter glutamate. CBD has similar effects on the brain. However, prefrontal GABA systems responded in a different way in ASD than in ‘neurotypical’ participants, which prompted researchers to further explore CBDV effects on ASD. CBDV And Intractable Epilepsy Intractable epilepsy or drug-resistant epileptic seizures is a condition where seizures aren’t managed with medication easily. Before Epidoliex was launched by GW Pharmaceuticals, the company supported clinical trials seeing Cannabidivarin as an anticonvulsant. The trials showed that CBDV matched the effects of CBD as an anticonvulsant. The anti-epileptic working of CBDV and CBD are believed to be due to their desensitization of the TRPV1 (vanilloid) receptor. This receptor gets involved in the onset and progression of several kinds of epilepsy. CBDV showed promise in managing chemically induced seizures. However, the next stage of these trials didn’t bring much success. Since then, GM Pharmaceuticals has been concentrating on CBDV’s abilities towards ASD rather than as a treatment for seizures. CBDV And Nausea Symptoms You already know that nausea is one of the human body’s highly evolved defense mechanisms to rid it of potentially dangerous substances. This mechanism often gets taken over by various lifestyle factors such as stress or side-effects from common medicines. A study looked at THCV’s and CBDV effects at inducing nausea and concluded that it had the opposite effect in rats. CBDV And Duchenne Muscular Dystrophy (DMD) DMD (Duchenne Muscular Dystrophy) is a genetic issue that’s known by progressive muscle degeneration from dystrophin protein deficiency, which shields the integrity of muscle cells, leading to inflammation and irreversible skeletal muscle degeneration. Currently, there is no cure for this condition, but steroidal medicine and physical therapy help to keep symptoms in check. The National Research Council (Italy) investigated non-euphoric compounds from cannabis plants, specifically Cannabidivarin, CBD, and THCV to relieve inflammation and support muscle functioning. In this study, researchers found that both CBDV and CBD enhanced myotube formation and relieved inflammation. CBDV and Rett Syndrome (RTT) RTT (Rett Syndrome) is a neurological disease that is found only in girls. It’s caused by a rare gene mutation and causes severe impairments such as loss of speech and muscle coordination. Currently, there is no cure for Rett syndrome, so treatments are aimed at reducing anxiety and social deficit symptoms to enhance the quality of life of those dealing with RTT. In clinical trials, researchers found that Cannabidivarin given to mice … Read more